产品目录

分子量：Approximately 9.1kDa,a single non-glycosylated polypeptide chain containing 78 amino acids.
储存条件：冷冻（-20℃）

概述

Interleukin-8(IL-8)is encoded by the IL8 gene and produced by macrophages and other cell types such as epithelial cells.It is also synthesized by endothelial cells,which store IL-8 in their storage vesicles.There are many receptors capable to bind IL-8,the most affinity to IL-8 are receptors CXCR1,and CXCR2.As a member of the CXC chemokine family,function of IL-8 is the induction of chemotaxis in its target cells,like neutrophil granulocytes,basophils,and T-cells.IL-8 is often associated with inflammation and has been cited as a proinflammatory mediator in gingivitis and psoriasis.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 20-200ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 2×PBS,pH 7.4.
内毒素	Less than 1 EU/ug of rPoIL-8/CXCL8 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	ARVSAELRCQ CINTHSTPFH PKFIKELRVI ESGPHCENSE IIVKLVNGKE VCLDPKEKWV QKVVQIFLKR TEKQQQQQ

相关搜索：重组猪IL-8/CXCL8，IL-8/CXCL8, Porcine，Recombinant Porcine Interleukin-8/CXCL8